Thematic plan of lectures on pharmacology
for students of the 3rd year of Faculty of Pharmacy (international batch)
for the 5th semester of 2024-2025 academic year
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Topic
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1
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Antihypertensives
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2
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Heart Failure
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3
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Antiarrhythmics
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4
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Anticoagulants and Antiplatelet Agents
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5
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Pituitary and Thyroid
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6
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Drugs for Diabetes
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7
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Estrogens and Androgens
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8
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Drugs for Disorders of the Respiratory System
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Thematic plan of lectures on pharmacology
for students of the 3rd year of Faculty of Pharmacy (international batch)
for the 5th semester of 2024-2025 academic year
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Topic
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1
|
Antihypertensives
|
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2
|
Diuretics
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3
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Heart Failure
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4
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Antiarrhythmics
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5
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Antianginal Drugs
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6
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Anticoagulants and Antiplatelet Agents
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7
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Drugs for Hyperlipidemia
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8
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Test 4 Drugs Affecting the Cardiovascular System
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9
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Pituitary and Thyroid
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10
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Drugs for Diabetes
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11
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Estrogens and Androgens
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12
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Adrenal Hormones
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13
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Test 5 Drugs Affecting the Endocrine System
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14
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Drugs for Disorders of the Respiratory System
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15
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Antihistamines
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Thematic plan of lectures on Clinical Pharmacology
for students of the 4th year of Faculty of Pharmacy (international batch)
for the 7th semester of 2024-2025academic year
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Topic
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1
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Development & Regulation of Drugs
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2
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Nitric Oxide
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3
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Drugs of Abuse
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4
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Agents Used in Anemias; Hematopoietic Growth Factors
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5
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Agents That Affect Bone Mineral Homeostasis
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Thematic plan of practical classes on Clinical Pharmacology
for students of the 4th year of Faculty of Pharmacy (international batch)
for the 7th semester of 2024-2025 academic year
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Topic
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1
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Development & Regulation of Drugs
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2
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Development & Regulation of Drugs
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3
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Histamine, Serotonin, & the Ergot Alkaloids
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4
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Histamine, Serotonin, & the Ergot Alkaloids
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5
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Vasoactive Peptides
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6
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Vasoactive Peptides
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7
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The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
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8
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The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
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9
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Nitric Oxide
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10
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Nitric Oxide
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11
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Test 1
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12
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Test 1
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13
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The Alcohols
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14
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The Alcohols
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15
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Drugs of Abuse
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16
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Drugs of Abuse
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Thematic plan of lectures on pharmacology
for students of the 3rd year of Faculty of Pharmacy (international batch)
for the 5th semester of 2023-2024 academic year
|
|
Topic
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Date
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1
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Antihypertensives
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14.09.23
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2
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Heart Failure
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28.10.23
|
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3
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Antiarrhythmics
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12.10.23
|
|
4
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Anticoagulants and Antiplatelet Agents
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26.10.23
|
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5
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Pituitary and Thyroid
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9.11.23
|
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6
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Drugs for Diabetes
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23.11.23
|
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7
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Estrogens and Androgens
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7.12.23
|
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8
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Drugs for Disorders of the Respiratory System
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21.12.23
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Thematic plan of lectures on pharmacology
for students of the 3rd year of Faculty of Pharmacy (international batch)
for the 5th semester of 2023-2024 academic year
|
|
Topic
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Date
|
|
1
|
Antihypertensives
|
04.09-10.09
|
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2
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Diuretics
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11.09-17.09
|
|
3
|
Heart Failure
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18.09-24.09
|
|
4
|
Antiarrhythmics
|
25.09-01.10
|
|
5
|
Antianginal Drugs
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02.10-8.10
|
|
6
|
Anticoagulants and Antiplatelet Agents
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9.10-15.10
|
|
7
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Drugs for Hyperlipidemia
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16.10-22.10
|
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8
|
Test 4 Drugs Affecting the Cardiovascular System
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23.10-29.10
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9
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Pituitary and Thyroid
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30.10-05.11
|
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10
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Drugs for Diabetes
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06.11-12.11
|
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11
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Estrogens and Androgens
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13.11- 19.11
|
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12
|
Adrenal Hormones
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20.11- 26.11
|
|
13
|
Test 5 Drugs Affecting the Endocrine System
|
27.11-03.12
|
|
14
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Drugs for Disorders of the Respiratory System
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04.12-11.10
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15
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Antihistamines
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11.12-17.12
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Thematic plan of lectures on Clinical Pharmacology
for students of the 4th year of Faculty of Pharmacy (international batch)
for the 7th semester of 2023-2024 academic year
|
|
Topic
|
Date
|
|
1
|
Development & Regulation of Drugs
|
9.09.23
|
|
2
|
Nitric Oxide
|
16.09.23
|
|
3
|
Drugs of Abuse
|
23.10.23
|
|
4
|
Agents Used in Anemias; Hematopoietic Growth Factors
|
30.10.23
|
|
5
|
Agents That Affect Bone Mineral Homeostasis
|
7.11.23
|
Thematic plan of practical classes on Clinical Pharmacology
for students of the 4th year of Faculty of Pharmacy (international batch)
for the 7th semester of 2023-2024 academic year
|
|
Topic
|
Date
|
|
1
|
Development & Regulation of Drugs
|
04.09-10.09
|
|
2
|
Development & Regulation of Drugs
|
11.09-17.09
|
|
3
|
Histamine, Serotonin, & the Ergot Alkaloids
|
18.09-24.09
|
|
4
|
Histamine, Serotonin, & the Ergot Alkaloids
|
25.09-01.10
|
|
5
|
Vasoactive Peptides
|
02.10-8.10
|
|
6
|
Vasoactive Peptides
|
9.10-15.10
|
|
7
|
The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
|
16.10-22.10
|
|
8
|
The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
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23.10-29.10
|
|
9
|
Nitric Oxide
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30.10-05.11
|
|
10
|
Nitric Oxide
|
06.11-12.11
|
|
11
|
Test 1
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13.11- 19.11
|
|
12
|
Test 1
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20.11- 26.11
|
|
13
|
The Alcohols
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27.11-03.12
|
|
14
|
The Alcohols
|
04.12-11.10
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15
|
Drugs of Abuse
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11.12-17.12
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16
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Drugs of Abuse
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18.12- 24.12
|
Thematic plan of lectures on Clinical Pharmacology
for students of the 5th year of Faculty of Pharmacy (international batch)
for the 9th semester of 2023-2024 academic year
|
|
Тема занятия
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Дата
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|
1
|
Therapeutic & Toxic Potential of Over-the-Counter Agents
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8.09.23
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2
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Dietary Supplements & Herbal Medications
|
22.09.23
|
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3
|
Important Drug Interactions & Their Mechanisms
|
6.10.23
|
Thematic plan of practical classes on clinical pharmacology
for students of the 5th year of Faculty of Pharmacy (international batch)
for the 9th semester of 2023-2024 academic year
|
|
Тема занятия
|
Дата
|
|
1
|
Special Aspects of Geriatric Pharmacology
|
04.09-10.09
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2
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Special Aspects of Geriatric Pharmacology
|
11.09-17.09
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3
|
Dermatologic Pharmacology
|
18.09-24.09
|
|
4
|
Dermatologic Pharmacology
|
25.09-01.10
|
|
5
|
Therapeutic & Toxic Potential of Over-the-Counter Agents
|
02.10-8.10
|
|
6
|
Therapeutic & Toxic Potential of Over-the-Counter Agents
|
9.10-15.10
|
|
7
|
Dietary Supplements & Herbal Medications
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16.10-22.10
|
|
8
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Dietary Supplements & Herbal Medications
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23.10-29.10
|
|
9
|
Rational Prescribing & Prescription Writing
|
30.10-05.11
|
|
10
|
Rational Prescribing & Prescription Writing
|
06.11-12.11
|
|
11
|
Important Drug Interactions & Their Mechanisms
|
13.11- 19.11
|
|
12
|
Important Drug Interactions & Their Mechanisms
|
20.11- 26.11
|
|
13
|
Test 5
|
27.11-03.12
|
|
14
|
Test 5
|
4.12 – 10.12
|
Exam regulation and exam assessment criteria
A positive mark on the exam is set in the interval 70-100 points. In case of non-appearance of the student the exam mark and the rating are not calculated.
Exam is held in the written form as testing of knowledge of all sections of pharmacology. The task contains questions about classifications, mechanisms of action, pharmacological effects, indications and contraindications, side effects of drugs, as well as questions of general pharmacology. The task contains 50 numbered items or incomplete statements followed by four answers or by completions of statement. Student selects one correct lettered answer or completion that is the best in each case.
Each correct answer – 2 points, maximal for all correct answers – 100 points.
The result of exam is also entered into the computer.
The final rating of the discipline is calculated after passing the exam and is announced
students on the day of the exam. The discipline rating is entered in the gradebook along with the assessment in accordance with traditional scale assessing the results of intermediate certification:
"fine" 90-100 points
"good" 80-89 points
"satisfactorily" 70-79 points
"unsatisfactory" 0-69 points
Written appeals can be made to the head of the department in
the day of the announcement of the final rating; appeal consideration and decision on it is made on the same day.
Re-examination of the pharmacology exam in the framework of the “Knowledge Rating Rating System students" in order to improve the assessment is carried out only with the permission of the Vice-Rector for educational activities of KSMU.
Exam Questions
1. The principles of classification of drugs. Sources of reference information on medicines.
2. Dosage of drugs. Dose classification.
3. The concept of pharmacodynamics and pharmacokinetics of drugs. Stages pharmacokinetics of drugs.
4. The main mechanisms of absorption of drugs. Examples. Bioavailability of drugs
5. Factors affecting the distribution of drugs in the body. Examples.
6. The metabolism of drugs in the body. Metabolism reactions of the 1st and 2nd phase. Examples.
7. Excretion of drugs from the body. Elimination of drugs, factors affecting it. Half-life of drugs.
8. Routes for administering drugs to the body. Examples.
9. Local and resorptive (systemic) effects of drugs. Examples.
10. Stimulating, exciting, sedative and inhibitory (depressing) effects of drugs. Examples.
11. Selective, predominant, general cellular effect of drugs. Examples.
12. Reversible and irreversible effect of drugs. Examples.
13. Direct, indirect and reflex action of drugs. Examples.
14. Types of drug therapy. Examples.
15. The mechanisms of action of drugs. The role of receptors in mediating effects of medicines. Examples. The concept of ligands, agonists and receptor antagonists. Examples.
16. Non-receptor mechanisms of action of drugs. Examples.
17. Synergism as an option for drug interactions with each other. Types of synergism. Examples. Clinical significance.
18. Antagonism as an option for drug interactions with each other. Examples. The use of drug antagonism in clinical practice.
19. The phenomena arising at repeated use of the same medicine. Tolerance, drug dependence and cumulation. Examples. Clinical significance.
20. Dependence of the action of drugs on age and other individual features and conditions of the body. Examples.
21. Incompatibility of medicinal substances: pharmaceutical and pharmacological. Examples.
22. Sources of drugs. Examples. Stages of creating and introducing new medicines.
23. Side effect of drugs. Options. Examples.
24. Cholinomimetic agents. Classification. M-cholinomimetics. Effects on various organs and tissues. Indications for use. Muscarin poisoning: causes, symptoms, treatment.
25. Anticholinesterase drugs. Mechanism of action. The main pharmacological effects. Indications for use. Side and toxic effects of anticholinesterase drugs. The treatment of poisoning.
26. H-cholinomimetics. Pharmacological effects. Indications for use. Toxic effect of nicotine.
27. M - anticholinergic drugs. Mechanism of action. Actions on organs with cholinergic innervation, on the central nervous system.Characteristics of individual drugs and their practical use. Action of M-anticholinergics on the eye, the use of these effects in medical practice. Symptoms of poisoning with M-anticholinergics. Treatment.
28. Ganglion blockers. Pharmacological effects. Indications for use. Possible complications and measures for their prevention.
29. Sceletal muscles relaxants. Classification. Mechanisms of action. Uses. Side effects.The interaction with anticholinesterase drugs.
30. Adrenomimetics. Classification. Mechanisms of action. Comparative characteristics of epinephrine, norepinephrine, isoprenaline and phenylephrine (spectrum of action of drugs on adrenergic receptors, features of pharmacological effects, indications and contraindications for use).
31. Indirect adrenomimetics. Mechanism of action, main pharmacological effects, indications and contraindications for use.
32. Adrenergic blockers. Classification. Pharmacological effects. Indications for use Side effects.
33. Sympatolytics. Mechanism of action. The main pharmacological properties, uses and side effects.
34. Sympatolytics. Mechanism of action. The main pharmacological properties, application and side effects.
35. General anesthestetics. Classification. The sequence of action on the central nervous system and stages of anesthesia. Comparative characteristics of inhalational anesthesetics. Side effects. Noninhalational anesthesetics.
Classification. Mechanisms of action. Individual drugs. Side effects. The concept of combined and potentiated anesthesia.
36. Ethanol. Effect on the central nervous system. Antimicrobial and irritating effects. Acute poisoning. Alcoholism, its social aspects.
37. Hypnotics (sleeping pills). Classification. Mechanisms of action. Side effects. The possibility of drug dependence. Acute poisoning, the principles of its treatment.
38. Antiepileptic drugs. The mechanisms of action of antiepileptic drugs. The use in different forms of epilepsy. Drugs used in epileptic status. Side effects of antiepileptic drugs.
39. Antiparkinsonian drugs. Basic principles of pharmacological correction of Parkinsonian disease.Classification and mechanism actions of antiparkinsonian drugs. The main side effects.
40. Narcotic analgesics (opioid analgesics). Classification. Morphine. The mechanism of analgesic action.Pharmacological effects on the CNS and internal organs. Indications for use. Side effects and contraindications. Addiction, drug dependence. Acute morphine poisoning,principles of treatment.
41. Comparative pharmacological characteristics of codeine, fentanyl and trimeperidine. Acute and chronic opioid poisoning, the principles of its treatment. Specific antagonists of opioid analgesics. Addiction: social significance, preventive measures and treatment.
42. Non-narcotic analgesics. Classification. Mechanism of action. Pharmacological effects, indications and contraindications for use. Side effect. Non-narcotic analgesics - selective COX-2 inhibitors. Features of the action. Indications for application. Contraindications The main side effects.
43. Antipsychotics. Classification. Mechanism of action, central and peripheral pharmacological effects. Comparative characteristics of Individual drugs. Indications. Side effects, their pharmacological correction. The concept of "neuroleptanalgesia."
44. Anxiolytics. Classification. Mechanisms of action. Comparative characteristics of individual drugs. Indications for use. Side effects. Drug dependence.
45. Psychostimulants. Classification. Mechanism of action, central and peripheral effects of caffeine. The effect of caffeine on the cardiovascular system. Indications. Side effects.
46. Antidepressants. Classification. Mechanisms of action. Indications for use. Side effects.
47. Nootropic drugs, memory enhancers. Pharmacological effects, indications for use.
48. Bronchodilators. Classification. The mechanisms actions, pharmacological effects of individual representatives. Side effects.
49. Antitussive drugs. Classification. Mechanisms of action. Indications and contraindications for use.
50. Expectorants. Classification. Mechanisms of action. Indications for use. Side effects. Mucolytics.
51. Cardiotonic drugs. Classification. Cardiac glycosides. Pharmacokinetics of cardiac glycosides. The mechanisms of action of heart. Preparations. Side effects. Indications for use.
52. Comparative characteristics of digitoxin, digoxin and strophanthine. The problem of the effectiveness and safety of cardiac glycosides. Cardiac glycoside intoxication, its treatment and prevention.
53. Antianginal drugs. Classification. The mechanism of action of nitroglycerin. Nitroglycerin of prolonged action, pharmacokinetics. Indications for the use. Side effects.
54. Antianginal drugs not belonging to the group of organic nitrates and nitrites.Mechanisms of action. Individual representatives. Side effects.
55. Hypolipidemic drugs. Classification. Pharmacological effects of individual representatives. Side effects.
56. Antiarrhythmic drugs. Classification. Mechanism of action. Indications for use. Side effects.
57. Drugs used in arterial hypotension. Mechanisms of action. Pharmacological effects. Indications for use. Side effects.
58. Antihypertensive drugs acting on renin-angiotensin system. Classification. The mechanisms actions. Individual drugs. Indications for use.
59. Antihypertensive drugs myotropic action. Classification. Mechanisms of action. Indications for their use. Side effects. The combined use of antihypertensive drugs.
60. Neurotropic antihypertensive drugs. Classification, pharmacological effects, side effects. The mechanism of action of clonidine. Typical side effects.
61. Diuretics. Classification. The mechanisms of action of diuretics. Indications for use. Side effects, their prevention. Spironolactone, its mechanism of action, pharmacological effects, uses. The mechanism of action and the use of osmotic diuretics.
62. Drugs acting on uterus. Classification. The mechanism of action and basic pharmacological effects. Uses. Side effects.
63. Drugs acting on blood formation. Classification. Haematinics. Drugs that affect leukopoiesis. Indications for use. Drugs used to treat hypochromic anemia and hyperchromic anemias. Mechanism of action. Uses. Side effects.
64. Blood coagulation aids. Classification. Hemostatic and antihemorrhagic agents. The mechanisms of action. Indicationsforuse.
65. Anticoagulants. Classification. Mechanism of action. Uses. Complications. Antagonists of anticoagulants, mechanism of action and use.
66. Drugs acting on fibrinolysis. Classification. Mechanism of action. Indications to use. Sideeffects.
67. Agents inhibiting platelet aggregation. Classification. Mechanisms of action various drugs. The use of antiplatelet agents. Sideeffects.
68. Drugs that affect appetite. Classification. Characteristics of individual representatives. Indications for use
69. Antacids and antisecretory drugs. Mechanisms of action, characteristics of the maingroups and their representatives. Indications for use. Side effects.
70. Enzymes and inhibitors of enzymes.Classification. Comparativecharacteristics of individual drugs. Indications for use. Side effects.
71. Laxatives Classification. Preferential localization, mechanism of action and comparative characteristics of individual drugs. Indications for use of individual groups of drugs. Antidiarrheal drugs. Localization of actions, acting principles and mechanism of action. Preparations and use. Side effects.
72. Cholagogue. Classification. The mechanism of action of funds that enhance bile formation. Useds. Side effects. Drugs increasing secretion of bile. Uses.
73. Vitamines. Classification. Vitamins C, P, PP. Basic pharmacological effects. Indications for use. Side effects. Vitamins B1, B2, B6. The main pharmacological effects. Indications for the use of individual drugs. Side effects and measures to prevent them.
74.Fat-soluble vitamins. Basic pharmacological effects. Indications for use. Side effects.
75. Pituitary hormone preparations. Classification. The main pharmacological properties and the use of tropic hormones of the anterior pituitary gland. Side effects. Hormones of the posterior pituitary gland. Mechanisms of action and basic pharmacological properties Practical use. Side effects.
76. Thyroid hormone preparations and antithyroid drugs. Mechanism of action and the effect on the metabolism of thyroid hormone preparations. Uses. Sideeffects. Antithyroid drugs. Mechanisms of action. Uses. Side effects.
77. Antidiabetic agents. Classification. Insulin. Mechanism of action. Comparative evaluation of insulin preparations. Dosing of insulin, individual selection of doses and their regimens of use. Hypoglycemic and hyperglycemic conditions as complications of treatment diabetes. Oral hypoglycemic agents. Classification. Mechanisms of action. Preparations. Side effects.
78. Adrenal cortex hormone preparations. Classification. Glucocorticoids. Mechanism actions. The main pharmacological effects. Comparative haracteristics of individual preparations. Indications for use. Side effects. Contraindications
79. Female sex hormones and their synthetic analogues. Mechanism of action.Indications for use. Side effects. Hormonal birth control. Classification. The mechanism of their contraceptive action. Application. Side effects. Antagonists of female sex hormones.
80. Preparations of male sex hormones and their synthetic analogues. Mechanism of action. The main pharmacological properties. Indications for use. Side effects.Antagonists of male sex hormones.
81. Immunotropic drugs. Classification. Possible mechanisms of action. Indications for use. Complications
82. Antiallergic drugs. Classification. Mechanisms of action. Comparative assessment individual drugs. Application. Sideeffects.
83. Antiseptic and disinfectants. Classification. Mechanisms of action. Pharmacological effects of individual representatives. Uses.
84. Penicillin antibiotics. Classification. The mechanism of antimicrobial action. Biosynthetic penicillins, spectrum of action. Semi-synthetic penicillins.Spectrum and mechanism antibacterial action. Use. Side effects.
85. Cephalosporins. Classification. Spectrum and mechanism of action. Side effects. Uses.
86. Antibiotics – carbapenems and monobactams. Spectra and mechanisms of their antimicrobial actions. Indication. Side effects.
87. Antibiotics of the aminoglycoside group. The spectrum and mechanism of antimicrobial action. Features of the action of individual drugs. Indications for use. Side effects.
88. Antibiotics – macrolides. The mechanism and spectrum of action. Azalides, their features. Indications for use. Side effects.
89. Antibiotics – tetracyclines and chloramphenicol. The spectrum and mechanism of antimicrobial action. Characteristic features of the action of individual drugs. Indications for use. Side effects.
90. Sulfanilamide preparations. Classification. Pharmacokinetics of sulfonamides. Mechanism and spectrum of antibacterial action. Combined sulfanilamide drugs. Side effects, their prevention and treatment.
91. Derivatives of nitrofuran and oxyquinoline. Spectra and mechanisms of antibacterial actions. Indications for use. Side effects.
92. Quinolones and fluoroquinolones. Representatives. Mechanisms of action. Indications for use. Characteristic side effects.
93. Anthelmintic. Classification. Mechanisms of action. Basic principles of use. Comparative characteristics of individual drugs. Side effects.
94. Antifungal agents. Classification. Mechanisms of action. Antifungal antibiotics. Indications for use.
95. Antimalarial drugs. Classification. Mechanism of action. Action for various forms of malarial plasmodium. Comparative characteristics of drugs, their toxicity and side effects.
96. Antiviral agents. Classification. Mechanisms of action. Indications for use. Side effects.
97. Treatment for syphilis and gonorrhea. Features of the mechanism of action and effects of individual preparations. Side effects.
98. Anti-TB drugs. Classification. Spectrum and mechanisms of antibacterial actions. Features of the use of anti-tuberculosis drugs. Side effects. Medical and social aspects of anti-TB treatment.
99. Antineoplastic agents. Classification. Mechanisms of action. Characteristic side effects of individual representatives.
100. The basic principles of the treatment of acute drug poisoning. Antidotes. Examples
Examination Appeal Procedure
The student has the right to file a written appeal with the head of the dean's office (institute) about a violation, in his opinion, of the established examination procedure and (or) disagreement with the exam results. The appeal is submitted by the student personally no later than the next business day after the announcement of the results of the exam.
To consider the appeal on the proposal of the head of the dean’s office (institute), by order of the vice-rector for educational activities, an appeal commission shall be created in the amount of not less than 3 teachers, from among whom the chairman and secretary are appointed. The examiner cannot be included in the appeal panel.
An appeal no later than 3 working days from the date of its submission is considered at a meeting of the appeal commission, to which the student who has filed an appeal is invited. The student’s absence does not impede the meeting.
The decision of the appeal commission is brought to the attention of the student who filed the appeal, within 3 working days from the day of the meeting of the appeal commission. The fact that the student who filed the appeal is acquainted with the decision of the appeals commission is certified by the student’s signature.
When considering an appeal for violation of the examination procedure, the appeal commission takes one of the following decisions:
- on the rejection of the appeal, if the information contained in it about violations of the examination procedure has not been confirmed and (or) did not affect the exam result;
- on the satisfaction of the appeal, if the information contained in it about the committed violations of the examination procedure was confirmed and influenced the exam result. If the appeal is upheld, the exam result is subject to cancellation. The student is given the opportunity to pass the exam within the time period established by order of the rector for intermediate certification (including as part of another academic group) or to eliminate academic debt. Repeated examination is carried out in the presence of one of the members of the appeal commission.
When considering an appeal on disagreement with the results of the exam, the appeal commission makes one of the following decisions:
- On the rejection of the appeal and the preservation of the result of the exam;
- on the satisfaction of the appeal and setting a different exam result. In this case, the previously set exam result is canceled and a new one is set.
The decision of the appeals commission is final and not subject to review. An appeal for re-examination is not accepted.
Казанский государственный
